Repository logo
 
Publication

Folk medicinal plant extracts as a source of biomolecules with antifungal properties against Candida species

2015Conference object Open access
Simple item page
dc.contributor.authorMartins, Natália
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.contributor.authorCarvalho, Ana Maria
dc.contributor.authorHenriques, Mariana
dc.contributor.authorSilva, Sónia
dc.date.accessioned2015-10-27T16:23:23Z
dc.date.available2015-10-27T16:23:23Z
dc.date.issued2015
dc.description.abstractIncreasing rates of opportunistic fungal infections and microorganisms with drug-resistance have been observed. Candida species are the most common pathogens, considered the fourth leading cause of hematogenous infections. Thus, it is crucial to discover alternatives to the current antifungal agents. Healing properties of medicinal plants are widely recognized, but some properties and the related mechanisms of action remain unknown. Therefore, the anti-Candida potential of hydromethanolic extracts obtained from ten folk medicinal plants (Echinacea purpurea L.; Eucalyptus globulus Labill.; Foeniculum vulgare Mill.; Juglans regia L.; Matricaria recutita L.; Melissa officinalis L.; Pterospartum tridentatum L.; Rosa canina L.; Rubus ulmifolius L. and Tabebuia impetiginosa L.) was evaluated, by using Disc Diffusion Assay and determination of minimal inhibitory concentrations by microdilution method. J. regia was the most effective, inhibiting the growth of the tested nineteen Candida strains (halo diameter varying between 9-14 mm) and causing a growth reduction of 3-5 Log (CFUs) for Candida parapsilosis and C. tropicalis, and 0.5-2.5 for C. albicans and C. glabrata. E. globulus also exhibit a significant potential, being effective against seventeen Candida strains (halo diameter ranging between 9-21 mm) and causing a growth reduction of 2-5 Log (CFUs). P. tridentatum and R. ulmifolius showed similar antifungal effects, being effective against six Candida strains (halo diameter ranging between 9-19 mm). So, as main conclusions, hydromethanolic extracts of E. globulus and J. regia could constitute promissory alternatives to the current antifungal agents, but more detailed studies are needed in order to identify the bioactive compounds and related mechanism of action.pt_PT
dc.identifier.citationMartins, Natália; Ferreira, Isabel C.F.R.; Barros, Lillian; Carvalho, Ana Maria; Henriques, Mariana; Silva, Sónia (2015). Folk medicinal plant extracts as a source of biomolecules with antifungal properties against Candida species. In International Conference on Antimicrobial Agents and Chemoterapy. Sevillapt_PT
dc.identifier.urihttp://hdl.handle.net/10198/12208
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleFolk medicinal plant extracts as a source of biomolecules with antifungal properties against Candida speciespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.titleInternational Conference on Antimicrobial Agents and Chemoterapypt_PT
person.familyNameFerreira
person.familyNameBarros
person.familyNameCarvalho
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.givenNameAna Maria
person.identifier144781
person.identifier469085
person.identifierID G-7399-2011
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idD31A-35AF-E2A9
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0001-5508-5935
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id20336503900
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication977f5254-f7c5-4c91-873f-2700ecd4692f
relation.isAuthorOfPublication.latestForDiscovery3af07ffe-f914-48ba-a5d5-efcf70fdce01

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Poster Int. 162.pdf
Size:
231.07 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIMO - Resumos em Proceedings Não Indexados à WoS/Scopus