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Research Project
Study of bioactivities of edible Microalgae extracts
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Sulfur-containing compounds from plants
Publication . Castro, Vera; Carpena Rodríguez, María; Fraga-Corral, Maria; Lopez-Soria, A.; Garcia-Perez, Pascual; Barral Martínez, Marta; Perez-Gregorio, R.; Cao, Hui; Simal-Gandara, Jesus; Prieto Lage, Miguel A.
Sulfur (S) is an essential nutrient assimilated through the diet and incorporated
into organic structures such as amino acids, coenzymes, and other bioactive
compounds. Plants’ ability to regulate stress resistance via secondary metabolism has extended the interest in S-containing compounds, driven by their additional
properties as bioactive molecules. Among plant families that produce S-compounds,
the Brassicaceae, which includes broccoli, cabbage, and cauliflower, and the
Liliaceae family, which includes garlic and onion, stand out. In recent years, the
research has been focused on S-containing amino acids (mainly methionine and
cysteine) and glucosinolates (GSLs) and their hydrolysis products like
isothiocyanates but also in other S-containing compounds such as phytoalexins or
cysteine sulfoxides. GSLs are becoming more popular because of their specific
biological properties, including antioxidant, anti-inflammatory, or antimicrobial,
among others. Accordingly, a diet rich in vegetables containing S-containing compounds
has been associated with a lower risk of developing cancer, neurological
diseases like Alzheimer’s, inflammatory bowel disease, cardiovascular diseases,
several skin disorders, and obesity. Hence, S-metabolites can therefore be used as
therapeutic and preventative components in functional foods and nutraceuticals, as
well as cosmeceutical products. This chapter aims to revise the most important
features related to sulfur metabolism and S-containing compounds from plant
sources, with emphasis on their involvement in secondary metabolism, natural
sources, structural classification, biological functions, and applications in human
nutrition and health.
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Fundação para a Ciência e a Tecnologia
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Funding Award Number
PD/BD/150264/2019
