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Projeto de investigação
Safety of Plant Food Supplements: advanced genomic and chemical approaches to assess botanical origin, illegal drugs and contaminants
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Mass spectrometry‐based approaches to assess the botanical authenticity of dietary supplements
Publication . Grazina, Liliana; Mafra, Isabel; Monaci, Linda; Amaral, Joana S.
Dietary supplements are legally considered foods despite frequently including
medicinal plants as ingredients. Currently, the consumption of herbal dietary
supplements, also known as plant food supplements (PFS), is increasing worldwide
and some raw botanicals, highly demanded due to their popularity,
extensive use, and/orwell-established pharmacological effects, have been attaining
high prices in the international markets. Therefore, botanical adulteration
for profit increase can occur along the whole PFS industry chain, from raw
botanicals to plant extracts, until final PFS. Besides the substitution of highvalue
species, unintentional mislabeling can happen in morphologically similar
species. Both cases represent a health risk for consumers, prompting the development
of numerous works to access botanical adulterations in PFS. Among
different approaches proposed for this purpose, mass spectrometry (MS)-based
techniques have often been reported as the most promising, particularly when
hyphenated with chromatographic techniques. Thus, this review aims at describing
an overview of the developments in this field, focusing on the applications
of MS-based techniques to targeted and untargeted analysis to detect botanical
adulterations in plant materials, extracts, and PFS.
Mass spectrometry‐based approaches to assess the botanical authenticity of dietary supplements
Publication . Grazina, Liliana; Mafra, Isabel; Monaci, Linda; Amaral, Joana S.
Dietary supplements are legally considered foods despite frequently including
medicinal plants as ingredients. Currently, the consumption of herbal dietary
supplements, also known as plant food supplements (PFS), is increasing worldwide
and some raw botanicals, highly demanded due to their popularity,
extensive use, and/orwell-established pharmacological effects, have been attaining
high prices in the international markets. Therefore, botanical adulteration
for profit increase can occur along the whole PFS industry chain, from raw
botanicals to plant extracts, until final PFS. Besides the substitution of highvalue
species, unintentional mislabeling can happen in morphologically similar
species. Both cases represent a health risk for consumers, prompting the development
of numerous works to access botanical adulterations in PFS. Among
different approaches proposed for this purpose, mass spectrometry (MS)-based
techniques have often been reported as the most promising, particularly when
hyphenated with chromatographic techniques. Thus, this review aims at describing
an overview of the developments in this field, focusing on the applications
of MS-based techniques to targeted and untargeted analysis to detect botanical
adulterations in plant materials, extracts, and PFS.
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Fundação para a Ciência e a Tecnologia
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Número da atribuição
COVID/BD/152444/2022