Browsing by Author "Gavan, Alexandru"
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- Development of an optimized drying process for the recovery of bioactive compounds from the Autumn Fruits of Berberis vulgaris L. and Crataegus monogyna JacqPublication . Moldovan, Cadmiel; Frumuzachi, Oleg; Babotă, Mihai; Menghini, Luigi; Cesa, Stefania; Gavan, Alexandru; Sisea, Cristian R.; Tanase, Corneliu; Dias, Maria Inês; Pereira, Carla; Ferreira, Isabel C.F.R.; Crişan, Gianina; Mocan, Andrei; Barros, LillianHot air drying has proven to be an efficient method to preserve specific edible plant materials with medicinal properties. This is a process involving chemical, physical, and biological changes in plant matrices. Understanding these processes will lead to an improvement in the yields of bioactive compounds. This study aims to optimize the drying process of two species’ fruits used in folk medicine, Berberis vulgaris and Crataegus monogyna. The optimized extracts’ antioxidant capacity was assessed using various assays, with the barberry extract showing very good activity (50.85, 30.98, and 302.45 mg TE/g dw for DPPH, TEAC, and FRAP assays, respectively). Both species exerted good fungal α-glucosidase inhibitory activity (IC50 = 0.34 and 0.56 mg/mL, respectively) but no activity on mammalian α-glucosidase. Additionally, this study identified and quantified the main bioactive compounds. The results presented herein are a breakthrough in industrializing this drying process. Additional studies are necessary to mechanistically understand the drying process involved in these plant materials.
- Optimization of the drying process of autumn fruits rich in antioxidants: A study focusing on rosehip (: Rosa canina L.) and sea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson) and their bioactive propertiesPublication . Moldovan, Cadmiel; Babotă, Mihai; Mocan, Andrei; Menghini, Luigi; Cesa, Stefania; Gavan, Alexandru; Sisea, Cristian R.; Vodnar, Dan C.; Dias, Maria Inês; Pereira, Carla; Ferreira, Isabel C.F.R.; Crisan, Gianina; Barros, LillianNowadays, it is very important to identify the traditional uses of different plants and to create the context in which new cultural or economic value is given to local resources. In this study, two wild fruits traditionally harvested in autumn in Romania were selected to investigate the effects of drying conditions on the chemical compositions and bioactivities exerted by the extracts and to select the best conditions in terms of air temperature and time of drying. The extracts obtained were assessed in terms of antioxidant capacity and enzyme inhibitory activity, and their main bioactive compounds were identified and quantified. The data presented in this article represent a step forward in applying this process on an industrial-scale. This journal is