Percorrer por autor "Garcia Perez, Pascual"
A mostrar 1 - 2 de 2
Resultados por página
Opções de ordenação
- Authenticity and Bioactive Markers Search in the Phenolic‐Rich Extracts of Asteraceae Medicinal Plants Through Integrative Computational ChemometricsPublication . Garcia Perez, Pascual; Garcia‐Oliveira, Paula; Finimundy, Tiane C.; Pinela, José; Calhelha, Ricardo C.; Nenadić, Marija; Soković, Marina; Simal‐Gandara, Jesus; Barros, Lillian; Prieto Lage, Miguel A.The Asteraceae family has been of significant concern for ethnobotanical studies, thanks to its health-promoting properties linked to a plethora of bioactive compounds, among which phenolic compounds play a critical role. In this work, a workflow based on computational chemometrics was employed to assess the authenticity and biomarker search of five key Asteraceae species commonly employed in traditional medicine. The UHPLC-DAD- ESI/ MS–MS phenolic profile of Asteraceae extracts was combined with the evaluation of several in vitro biological properties. Caffeoylquinic acids (CQAs), chicoric acids, and flavonoid glycosides were reported as authenticity markers of Achillea millefolium, Taraxacum officinale, and Arnica montana, respectively. The integration of phenolic profile and in vitro bioactivities provide insights for the identification of trans 3,5-O- dicaffeoylquinic acid (3,5-O- diCQA) and isorhamnetin glycosides as the major antioxidant agents in Asteraceae extracts, whereas several CQAs and caffeoyl-deoxy- octulopyranosonic acids have been reported as responsible for their cytotoxic and anti-inflammatory activities. These results shed light on the authentication and quality evaluation of Asteraceae extracts, along with the characterization of their functional properties, leading to their application in the design of novel plant-based functional foods.
- Evaluation of macroalgae as a source of nutrients for nutraceutical foodsPublication . García-Oliveira, Paula; Carreira Casais, Anxo; Pereira, Eliana; Caleja, Cristina; Barral Martínez, Marta; Garcia Perez, Pascual; Barros, Lillian; Prieto Lage, Miguel A.; Simal-Gandara, Jesus; Ferreira, Isabel C.F.R.Macroalgae are responsible for most of the production in aquatic ecosystems, playing an important role in the biosphere [1]. Although the consumption of macroalgae as foods is typical of Asian countries, these products are gaining popularity in Europe and North America [2]. Macroalgae are known for their excellent nutritional value, specially due to their high levels of protein and low lipid and caloric content. Furthermore, they are rich in numerous bioactive compounds, such as vitamins, essential fatty acids and phenolic compounds, which have been demonstrated to provide important health benefits to consumers [3]. This work aims to determine proteins, fat ash, carbohydrates and energy contents, and also the composition in organic acids and fatty acids of some seaweeds species, namely Himanthalia elongata L., S.F. Gray; Laminaria ochroleuca Bach.Pyl.; Saccharina latissima L.; Porphyra sp. C.Agardh; and Palmaria palmata (L.) Kuntze. The nutritional aspects were determined using official methodologies for food analysis, while organic acids by UPFLC-PDA and fatty acids by GC-FID. Proteins where the main macronutrients present with values ranging between 6 and 30 g/100 g of dry weight (dw) for S. latissima and Porphyra sp., respectively. On the other hand, a low lipid content was evident in all the studied seaweed species with values below 1 g/100 g dw. The energy values ranged from 218 and 370 kcal/100 g dw for L. ochrouleuca and Porphyra sp, respectively. Furthermore, several compounds of interest were identified. Among organic acids, oxalic acid was the only molecule present in all species. Regarding fatty acid content, saturated, unsaturated and polyunsaturated fatty acids were also determined, showing a clear heterogeneity of concentrations depending on the species. To conclude, the present study demonstrates the great potential of the selected macroalgae as source of non-animal protein and also some molecules with interesting properties. Thus, the incorporation of this macroalgae in the daily diet will have several benefits for consumers.