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Phenolic profile of Helichrysum stoechas L. Moench

2013Conference object Open access
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dc.contributor.authorBarroso, Marisa
dc.contributor.authorBarros, Lillian
dc.contributor.authorDueñas, Montserrat
dc.contributor.authorCarvalho, Ana Maria
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2013-09-09T14:24:24Z
dc.date.available2013-09-09T14:24:24Z
dc.date.issued2013
dc.description.abstractNatural matrices represent a rich source of biologically active compounds and are an example of molecular diversity, with recognized potential in drug discovery and development. Many plants frequently used in folk medicine have antioxidant and pharmacological properties connected with the presence of phenolic compounds, especially flavonoids [1]. The biological, pharmacological and medicinal properties of this group of compounds have been extensively reviewed (2]. Ethnobotanical surveys conducted in the Northeast of Portugal highlighted the decoction of Helichrysum stoechas (L.) Moench (shrubby everl asting; port. douradinha) for cold, bronchitis and fever [3]. In the present study, the phenolic composition of H. stoechas (inflorescences and leafy flowering stems) was analyzed by reversed-phase high performance liquid chromatography coupled to diode array detection and mass spectrometry with electron spray ionization (HPLC-DAD-ESI/MS), after extraction with methanol:water (80:20 v/v). Seventeen different phenolic compounds were identified, in which eight were characterized as phenolic acids, being 5-0-caffeoylquinic and 3,5-0-dicaffeoylquinic acids the most abundant compounds. Furthermore, nine flavonols were also identified, mostly derivatives of quercetin and myricetin, being myricetin 0 -acylhexoside the most abundant flavonoid. Overall, the analytical screening by HPLC-MS represents a valid and rapid approach in the search of new bioactive phenolic compounds.por
dc.description.sponsorshipFCT for financial support to CIMO (strategic project PEstOE/ AGR/UI0690/2011 ). L. Barros also thanks to FCT, POPH-QREN and FSE for her grant (SFRH/BPD/4609/2008). The GIP-USAL is financially supported by the Spanish Government through the Conso/ider-lngenio 2010 Programme (FUN-C-FOOD, CSD2007-00063). M. Duenas thanks to the Programa Ram6n y Cajal for a contract.por
dc.identifier.citationBarroso, Marisa; Barros, Lillian; Dueñas, Montserrat; Carvalho, Ana Maria; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2013). Phenolic profile of Helichrysum stoechas L. Moench. In 1st Symposium on Medicinal Chemistry. Bragapor
dc.identifier.urihttp://hdl.handle.net/10198/8685
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationPEstOE/AGR/UI0690/2011
dc.relationSFRH/BPD/4609/2008
dc.titlePhenolic profile of Helichrysum stoechas L. Moenchpor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceBraga, Portugalpor
oaire.citation.title1st Symposium on Medicinal Chemistry of University of Minhopor
person.familyNameBarros
person.familyNameCarvalho
person.familyNameFerreira
person.givenNameLillian
person.givenNameAna Maria
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifierID G-7399-2011
person.identifier144781
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idD31A-35AF-E2A9
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0001-5508-5935
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id20336503900
person.identifier.scopus-author-id36868826600
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication977f5254-f7c5-4c91-873f-2700ecd4692f
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscoverybd0d1537-2e03-41fb-b27a-140af9c35db8

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