Calhelha, Ricardo C.Campos, Joana F.Peixoto, DanielaAbreu, Rui M.V.Ferreira, Isabel C.F.R.Queiroz, Maria João R.P.2013-09-092013-09-092013Calhelha, Ricardo C.; Campos, Joana; Peixoto, Daniela; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R.P. (2013). Synthesis and evaluation of the antitumor potential of new aminated or methoxylated di(hetero)arylthioethers in the thieno[3,2-b]pyridine séries. In 1st Symposium on Medicinal Chemistry. Bragahttp://hdl.handle.net/10198/8684Synthesis and evaluation of the antitumor potential of new aminated or methoxylated di(hetero)arylthioethers in the thieno[3,2-b]pyridine séries. In 1st Symposium on Medicinal Chemistry. Braga Several thienopyridines have already been described as inhibitors of cell proliferation using human tumor cells[1,2], highlighting the interest of studying their antitumorpotential. ln this work, we present the synthesis of di(hetero)arylthioethers 1a-fby SNAr of the 7-chloro thieno[3,2- b]pyridine with amino or methoxy thiophenols in good to high yields, like presented in the scheme.engSynthesis and evaluation of the antitumor potential of new aminated or methoxylated di(hetero)arylthioethers in the thieno[3,2-b]pyridine seriesconference object