Kungel, Pâmela T.A.N.Correa, Vanesa G.Corrêa, Rúbia C.G.Peralta, Rosely AparecidaSoković, MarinaCalhelha, Ricardo C.Bracht, AdelarFerreira, Isabel C.F.R.Peralta, Rosane M.2018-02-192018-07-312018-01-192018-07-312018Kungel, Pâmela T.A.N.; Correa, Vanesa G.; Corrêa, Rúbia C.G.; Peralta, Rosely Aparecida; Soković, Marina; Calhelha, Ricardo C.; Bracht, Adelar; Ferreira, Isabel C.F.R.; Peralta, Rosane M. (2018). Antioxidant and antimicrobial activities of a purified polysaccharide from yerba mate (Ilex paraguariensis). International Journal of Biological Macromolecules. ISSN 0141-8130. 114, p. 1161-11670141-8130http://hdl.handle.net/10198/17477This study investigated the antioxidant, antimicrobial and cytotoxic properties of a purified yerba mate polysaccharide. The yerba mate polysaccharide showed a prominent antioxidant activity as evaluated by 2,2-diphenyl-1- picrylhydrazyl (DPPH•)-radical scavenging activity (IC50 = 1.25 ± 0.10 mg/mL), 3-ethyl benzothiazoline-6- sulphonic acid (ABTS•+)-radical scavenging activity (IC50 = 0.41 ± 0.05 mg/mL), and hydroxyl scavenging activity (IC50= 3.36 ± 0.31 mg/mL). The antioxidant activity evaluated as the ferric ion reduction power (FRAP) and oxygen radical absorbance radical assay (ORAC), expressed as trolox equivalents,were 20.84±1.61 μMTE/- mg and 556.30± 12.83 μM TE/mg, respectively. The purified yerbamate polysaccharide presented high antimicrobial activity against several bacterial and fungal strains; however, no cytotoxicity against all four tumor human cell lines assessed.engAntimicrobial activityAntioxidant activityPolysaccharideYerba matejournal article10.1016/j.ijbiomac.2018.04.020