Queiroz, AnaFoureaux, Nathalia S.Carneiro, Eduardo V.Ribeiro, António E.Brito, Paulo2023-01-312023-01-312022Queiroz, Ana; Foureaux, Nathalia S.; Carneiro, Eduardo V.; Ribeiro, António E.; Brito, Paulo (2022). Optimization of estradiol monitoring in raw and treated wastewater samples by response surface methodology. In XXIInd SGEM GeoConference. Viennahttp://hdl.handle.net/10198/26705The ever-increasing use of endocrine disruptors compounds (EDCs), through pharmaceuticals such as synthetic estrogens, both in humans as well as in animals, are raising its concentration in the environment. Estradiol, also designed as 17β-Estradiol (see Fig. 1), belongs to the pharmaceutical class of steroid estrogens and was included in the “Watch List” since 2013 the Directive 2013/39/EU due to its potential risk to human health and environment. The low removal efficiency of estrogens by the conventional wastewater treatment plants (WWTPs), becomes a major source of their release into different aquatic matrices. Therefore, the occurrence and, more importantly, the destination of these compounds are matters of utmost importance towards a better public health. The aim of this work is the optimization of solid phase extraction/high performance liquid chromatography (SPE/HPLC) using the response surface methodology (RSM) to detect and quantify 17β-Estradiol in WWTPs effluents.engEstradiolResearch Subject Categories::TECHNOLOGYconference poster