Calhelha, Ricardo C.Peixoto, DanielaSoares, PedroAbreu, Rui M.V.Ferreira, Isabel C.F.R.Queiroz, Maria João R.P.2013-01-072013-01-072012Calhelha, Ricardo C.; Peixoto, Daniela; Soares, Pedro; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Queiroz, Maria João R.P. (2012). Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines. In XXIInd International Symposium on Medicinal Chemistry. Berlinhttp://hdl.handle.net/10198/7834Thienopyridine skeleton has been reported as havi ng inte resting biological activity, namely antitumorlll and antiangiogenic121 activities. Herein, we describe the synth esis of thienopyridine arylethers la-f in moderate to good yields by a copper-cata lyzed C- 0 coupling, using N,N-dimethylglycine as a ligand, of the 7-bromothieno[3,2-b]pyridine, also prepared with substituted phenols (see scheme).engconference object