Rodríguez Rama, José-LuisMallo, NataliaBiddau, MarcoFernandes, FranciscoMiguel, Trinidad deSheiner, LilachChoupina, AltinoLores, Marta2019-11-192019-11-192019Rama, J.L.R.; Mallo, N.; Biddau, M.; Fernandes, F.; Miguel de T.; Sheiner, L.; Choupina, Altino; Lores, M. (2019). Exploring the powerful phytoarsenal of white grape marc against bacteria and parasites causing significant diseases. In HERAKLION 2019: 7th International Conference on Sustainable Solid Waste Management. Crete Island, Greecehttp://hdl.handle.net/10198/19824Natural extracts containing high polyphenolic concentration possess antibacterial, antiparasitic and fungicidal activities. The present research characterises white grape marc, a winemaking by-product describing their physicochemical features and antimicrobial capacities. Main components of 2 different extracts generated were phenolic acids, flavan-3-ols and their gallates, and flavonols and their glycosides. As a result of this complex composition white grape marc extracts showed pronounced bioactivities with potential uses in agricultural, pharmaceutical and cosmetic industries, among others. Specifically, polyphenol compounds were extracted by using hydro-organic solvent mixtures from the by-product of Albariño white wines (Galicia, NW Spain) production. In the present work the “in vitro” antimicrobial activity of the bioactive extracts was evaluated using two different hydro-organic mixtures (HOL & HOP). The microorganisms tested included Gram positive and negative bacteria, two Apicomplexan parasite species and one Oomycota parasite. Microbial species investigated are causing agents of several human and animal diseases, such as foodborne illnesses (Bacillus cereus, Eschericha coli, Salmonella enterica), skin infections (Staphylococcus aureus), mastitis (Streptococcus uberis), parasite infections as Malaria (Plasmodium falciparum) or Toxoplasmosis (Toxoplasma gondii), and plant infections as "chestnut ink" in chestnuts or "root rot" in avocado, both diseases caused by Phytophthora cinnamomi. Both extracts verified activity against all the tested species demonstrating their potentiality to be used for the development of biocides to control a wide range of pathogenic agents; at the same time that they contribute to winemaking industry residues valorisationengGrape marcNatural extractPolyphenolsAntiparasiticAntibacterianWinemaking by-products valorisationconference object