Albuquerque, HélioSantos, Clementina M.M.Cavaleiro, JoséSilva, Artur2020-07-202020-07-202017Albuquerque, Hélio; Santos, Clementina M.M.; Cavaleiro, José; Silva, Artur (2017). Microwave-assisted synthesis of chromeno[3,4-b]xanthones and (benzo[c]cromenyl)chromones. In TRAMECH IX - Transmediterranean Colloquium on Heterocyclic Chemistry. Fez, Marrocoshttp://hdl.handle.net/10198/22488Following previous reports dealing with the reactivity of chromone derivatives in Diels-Alder reactions, series of novel (E)-2-[2-(prop-2-yn-1-yloxy)styryl]chromones and of 2-{(1E,3E)-4-[2- (prop-2-yn-1-yloxy)phenyl]buta-1,3-dien-1-yl}chromones were designed and synthesized through aldol condensation of 2-methylchromones with 2-propargyloxy(benzaldehyde and cinnamaldehyde), respectively. Both chromone derivatives were used as substrates in microwave-assisted intramolecular Diels-Alder reactions, affording chromeno[3,4-b]xanthones and (benzo[c]chromenyl)chromones. This is the first report involving chromone derivatives in intramolecular Diels-Alder reactions for the synthesis of new oxygen heterocycles, namely xanthones and flavones [1-2].engPropargyloxychromonesIntramolecular Diels-AlderFlavonesXanthonesMW - assisted organic transformationsconference object