Finimundy, Tiane C.Karkanis, AnestisFernandes, ÂngelaPetropoulos, Spyridon Α.Calhelha, Ricardo C.Petrović, JovanaSoković, MarinaRosa, EduardoBarros, LillianFerreira, Isabel C.F.R.2018-02-192020-06-222018-01-192020-06-222020Finimundy, Tiane C.; Karkanis, Anestis; Fernandes, Ângela; Petropoulos, Spyridon A.; Calhelha, Ricardo; Petrović Jovana; Soković, Marina; Rosa, Eduardo; Barros, Lillian; Ferreira, Isabel C.F.R. (2020). Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes. Food Chemistry. ISSN 0308-8146. 327, p. 1-80308-8146http://hdl.handle.net/10198/6142In this study, the chemical characterization and bioactive properties of S. minor cultivated under different fertilization rates (control, half rate and full rate) were evaluated. Twenty-two phenolic compounds were identified, including five phenolic acids, seven flavonoids and ten tannins. Hydrolysable tannins were prevalent, namely Sanguiin H-10, especially in leaves without fertilization (control). Roots of full-rate fertilizer (660 Kg/ha) presented the highest flavonoid content, mainly catechin and its isomers, whereas half-rate fertilizer (330 Kg/ha), presented the highest content of total phenolic compounds, due to the higher amount of ellagitannins (lambertianin C: 84 ± 1 mg/g of dry extract). Antimicrobial activities were also promising, especially against Salmonella typhimurium (MBC = 0.44 mg/mL). Moreover, root samples revealed activity against all tested cell lines regardless of fertilization rate, whereas leaves were effective only against HeLa cell line. In conclusion, S. minor could be a source of natural bioactive compounds, while fertilization could increase phenolic compounds content.engAntimicrobial activitiesEllagitanninsFertilizationFlavonoidsPhenolic acidsSanguisorba minor L.Small burnetTanninsjournal article10.1016/j.foodchem.2020.127043