Teixeira, TâniaDeusdado, Sérgio2011-05-182011-05-182011Teixeira, Tânia; Deusdado, Sérgio (2011). Experiments on computer assisted optimization of the escherichia coli fermentation process using Optferm. In Rocha, Miguel P.[e tal.] 5th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2011). Berlin: Springer-Verlag. p. 79-82. (Advances in Intelligent and Soft Computing; 93). ISBN 978-3-642-19913-4978-3-642-19913-4DOI: 10.1007/978-3-642-19914-1_11http://hdl.handle.net/10198/4378We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesses avoiding expensive experiments.engBioprocesses optimizationBioprocesses modelingconference object