Froufe, Hugo J.C.Abreu, Rui M.V.Ferreira, Isabel C.F.R.2011-02-232011-02-232008Froufe, Hugo; Abreu, Rui M.V.; Ferreira, Isabel C.F.R. (2008). Farnesoid X Receptor: docking model validation. In Ias Jornadas Nacionais de Genética e Biotecnologia. Vila Realhttp://hdl.handle.net/10198/3526Farnesoid X receptor (FXR) is a protein that was shown to be involved in controlling numerous metabolic pathways that include: maintaining bile acid, lipid and glucose homeostasis, preventing intestinal bacterial infection and modulating liver regeneration and tumorigenesis [1]. TI1e different roles played by FXR highlight potential new opportunities for using FXR as a drug target for different diseases [2]. ln this worl< we validate the use of FXR as a target for virtual docking simulation experiments.engconference object