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Title: Phenolic compounds and antimicrobial activity of olive (Olea europaea L. Cv. Cobrancosa) leaves.
Authors: Pereira, Ana Paula
Ferreira, Isabel C.F.R.
Marcelino, Filipa
Valentão, P.
Andrade, P.B.
Seabra, R.M.
Estevinho, Leticia M.
Bento, Albino
Pereira, J.A.
Keywords: Olive leaves
Phenolic compounds
Antibacterial activity
Antifungal activity
Issue Date: 2007
Publisher: MDPI International
Citation: Pereira, Ana Paula; Ferreira, Isabel C.F.R.; Marcelino, Filipa; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Estevinho, Leticia M.; Bento, Albino; Pereira, J.A. (2007) - Phenolic compounds and antimicrobial activity of olive (Olea europaea L. Cv. Cobrancosa) leaves. Molecules. ISSN 1420-3049. 12, p. 1153-1162
Abstract: We report the determination of phenolic compounds in olive leaves by reversedphase HPLC/DAD, and the evaluation of their in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely Gram positive (Bacillus cereus, B. subtilis and Staphylococcus aureus), Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae) and fungi (Candida albicans and Cryptococcus neoformans). Seven phenolic compounds were identified and quantified: caffeic acid, verbascoside, oleuropein, luteolin 7-O-glucoside, rutin, apigenin 7-O-glucoside and luteolin 4’-O-glucoside. At low concentrations olive leafs extracts showed an unusual combined antibacterial and antifungal action, which suggest their great potential as nutraceuticals, particulalry as a source of phenolic compounds.
Peer review: yes
ISSN: 1420-3049
Appears in Collections:PTV - Artigos em Revistas Indexados ao ISI/Scopus

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