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Title: Antioxidant and antimicrobial activities of aqueous extracts of Anthemis nobilis
Authors: Pereira, Sara I.
Cardoso, Susana M.
Pereira, Olívia R.
Domingues, M.R.M.
Ferreira, Fernanda M.
Keywords: Anthemis nobilis L.
Antimicrobial activity
Antioxidant effects
Issue Date: 2011
Publisher: Centro de Estudos Farmacêuticos
Citation: Pereira, Sara I.; Cardoso, Susana M.; Pereira, Olívia R.; Domingues, Maria R. M.; Ferreira, Fernanda M. (2011) - Antioxidant and antimicrobial activities of aqueous extracts of Anthemis nobilis. In Conferência Centro de Estudos Farmacêuticos. Coimbra
Abstract: Introduction: Anthemis nobilis L. (roman chamomille) is an autochthonous plant, very common in North America and in Iberian Peninsula territory. The yellow flower buttons of this plant are widely used in traditional medicine and thus, they are commonly found in herbal stores. Anthemis nobilis L. is used as a potential therapeutic agent for all body illnesses, in particular for fever, inflammatory processes, skin infections and as a tranquilizer (1). In accordance, the main goal of this work was the evaluation of A. nobilis therapeutic potential, with focus on its antioxidant and antimicrobial activities. Methodology: Aqueous extracts of A. nobilis button flowers were prepared by maceration with water at room temperature during 2 hours or by decoction. Both extracts were analysed by electrospray mass spectrometry in the negative mode and their phenolic content was determined by the Folin–Ciocalteu method (2). Antioxidant activity was evaluated through ABTS radical-scavenging activity (3),TBARS method (4) and red blood cells haemolysis (5). Potential antibacterial action of the two extracts was evaluated as the antibiogram potential, analyzing Staphyllococcus aureus and Escherichia coli growth. Results: The aqueous extracts (crude and decoccion) of A. nobilis button flowers showed high antioxidant activity, as evaluated by ABTS, TBARS and haemolysis of red blood cells assays. Moreover, this activity was higher for the decoction extract, in good agreement with its greater phenolic content. As revealed by the mass spectrometry analysis, the potent antioxidant ability of aqueous A. nobilis extracts can result from the presence of quinic acid and caffeic acid derivatives. In opposition, the two aqueous extracts of A. nobilis button flowers showed no inhibitory effect on the growth of S. aureus and E. coli (common Gram+ and Gram- bacteria), thus indicating that this plant is not is not suitable for the treatment of health problems associated to those microorganisms.
Peer review: yes
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