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Please use this identifier to cite or link to this item: http://hdl.handle.net/10198/6900

Título: Antioxidant capacity and toxicological evaluation of pterospartum tridentatum flower extracts
Autor: Ferreira, Fernanda M.
Dinis, Lia T.
Azedo, Pedro
Galhano, Cristina
Cardoso, Susana M.
Domingues, M.R.M.
Pereira, Olívia R.
Simões, Anabela
Palmeira, Carlos
Peixoto, Francisco
Palavras-chave: Antioxidant capacity
Oxidative phosphorylation
Cytotoxicity
Pterospartum tridentatum (L.) Willk.
Toxicologic evaluation
Phytotherapy
Issue Date: 2012
Editora: Taylor & Francis
Citação: Ferreira, Fernanda; Dinis, Lia; Azedo, Pedro; Galhano, Cristina; Cardoso, Susana; Domingues, M. Rosário; Pereira, Olívia R.; Simões, Anabela; Palmeira, Carlos; Peixoto, Francisco (2012) - Antioxidant capacity and toxicological evaluation of pterospartum tridentatum flower extracts. CyTA - Journal of Food. ISSN 1947-6337. 10:2, p. 92-102
Resumo: Pterospartum tridentatum Willk. (prickled broom) is an autochthonous plant, common in Portuguese territory. The yellow flowers are used in traditional medicine, as a potential cure for all body illnesses, mainly for throat irritation treatment or for diabetes, hypertension and hypercholesterolemia therapy.Despite its traditional use, no toxicological assessment has been performed as we know. A high antioxidant activity of P. tridentatum flower water extract was acessed in good agreement with its ESI-MS spectrum that revealed the presence of several flavonoids, as luteolin-O-(O-acetyl)-glucuronide, luteolin-O- glucuronide or isorhamnetin-O-hexoside. Mitocondrial respiratory rates (state 4, state 3 and FCCP-stimulated respiration) and respiratory indexes (respiratory control and P/O ratios) showed no consistent decrease of respiratory and phosphorylative efficiencies for the concentrations tested (up to 500 μg.mL-1). Cytotoxicity evaluation, using MTT assay, was reliable with the previous results. In conclusion, for the concentration range commonly used P. tridentatum flowers usage can be regarded as harmless and trustworthy.
Arbitragem científica: yes
URI: http://hdl.handle.net/10198/6900
Versão do Editor: http://www.tandfonline.com/loi/tcyt20
Appears in Collections:DTDT - Artigos em Revistas Indexados ao ISI

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