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|Title: ||Antioxidant capacity and toxicological evaluation of pterospartum tridentatum flower extracts|
|Authors: ||Ferreira, Fernanda M.|
Dinis, Lia T.
Cardoso, Susana M.
Pereira, Olívia R.
|Keywords: ||Antioxidant capacity|
Pterospartum tridentatum (L.) Willk.
|Issue Date: ||2012|
|Publisher: ||Taylor & Francis|
|Citation: ||Ferreira, Fernanda; Dinis, Lia; Azedo, Pedro; Galhano, Cristina; Cardoso, Susana; Domingues, M. Rosário; Pereira, Olívia R.; Simões, Anabela; Palmeira, Carlos; Peixoto, Francisco (2012) - Antioxidant capacity and toxicological evaluation of pterospartum tridentatum flower extracts. CyTA - Journal of Food. ISSN 1947-6337. 10:2, p. 92-102|
|Abstract: ||Pterospartum tridentatum Willk. (prickled broom) is an autochthonous plant, common
in Portuguese territory.
The yellow flowers are used in traditional medicine, as a potential cure for all body
illnesses, mainly for throat irritation treatment or for diabetes, hypertension and
hypercholesterolemia therapy.Despite its traditional use, no toxicological assessment has been performed as we know.
A high antioxidant activity of P. tridentatum flower water extract was acessed in good
agreement with its ESI-MS spectrum that revealed the presence of several flavonoids, as
luteolin-O-(O-acetyl)-glucuronide, luteolin-O- glucuronide or isorhamnetin-O-hexoside.
Mitocondrial respiratory rates (state 4, state 3 and FCCP-stimulated respiration) and
respiratory indexes (respiratory control and P/O ratios) showed no consistent decrease
of respiratory and phosphorylative efficiencies for the concentrations tested (up to 500
μg.mL-1). Cytotoxicity evaluation, using MTT assay, was reliable with the previous
results. In conclusion, for the concentration range commonly used P. tridentatum
flowers usage can be regarded as harmless and trustworthy.|
|Peer Reviewed: ||yes|
|Publisher version: ||http://www.tandfonline.com/loi/tcyt20|
|Appears in Collections:||DTDT - Artigos em Revistas Indexados ao ISI|
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