Utilize este identificador para referenciar este registo: http://hdl.handle.net/10198/3938
Título: Oxidative stress response in gill and liver of Liza saliens, from the Esmoriz-Paramos coastal lagoon, Portugal
Autor: Fernandes, Conceição
Fontaínhas-Fernandes, A.
Ferreira, M.
Salgado, Maria Antónia
Data: 2008
Editora: Springer Science
Citação: Fernandes, Conceição; Fontaínhas-Fernandes, A.; Ferreira, M.; Salgado, M.A. (2008) - Oxidative stress response in gill and liver of Liza saliens, from the Esmoriz-Paramos coastal lagoon, Portugal. Archives Environmental, Contamination and Toxicology. ISSN 0090-4341. 55:2, p. 262-269
Resumo: Tissue-specific responses against oxidative stress and lipid peroxidation were analyzed in wild adult mullet (Liza saliens) caught in the Portuguese coastal lagoon Esmoriz-Paramos. Parameters measured were catalase (CAT), superoxide dismutase (SOD), and glutathione- S-transferase (GST) activities in liver and gill tissues and lipid peroxidation. The enzyme activities were related to gill histopathological alterations, as well as to heavy metals (Cu and Zn) concentrations in these tissues. Gill epithelium of L. saliens showed histological alterations, such as epithelial hyperplasia resulting in lamellar fusion, epithelial lifting, vasodilatation, and lamellar aneurisms, with a prevalence ranging from 62% to 92%. The highest Cu content was found in liver (379 mg kg-1), while the highest Zn content was observed in gill (119 mg kg-1). SOD and CAT activities showed differences between gill and liver. The highest activities found were SOD in gill (10.1 U/mg protein) and CAT in liver (39.2 mmol/min/mg protein). In gill, CAT activity was negatively related to both Cu levels and gill lifting, while a positive relationship was found between SOD activity and fish age. The positive relationship between Cu and CAT activity in liver suggests that an increase in metabolic level is related to Cu-induced oxidative stress. The decrease in gill CAT activity can be due to osmotic stress caused by damaged gill epithelium. CAT activity in liver is an appropriate biomarker of oxidative stress in the Esmoriz-Paramos lagoon.
Peer review: yes
URI: http://hdl.handle.net/10198/3938
ISSN: 0090-4341
Aparece nas colecções:PTV - Artigos em Revistas Indexados ao ISI/Scopus

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
18 Artigo stress oxidativo2008.pdf265,98 kBAdobe PDFVer/Abrir    Acesso Restrito. Solicitar cópia ao autor!
18 Artigo stress oxidativo resumo.pdf122,33 kBAdobe PDFVer/Abrir


FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote Degois 

Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.