Biblioteca Digital do IPB >
Escola Superior Agrária >
Biologia e Biotecnologia >
BB - Resumos em Proceedings Não Indexados ao ISI/Scopus >
Please use this identifier to cite or link to this item:
|Título: ||In vitro growth inhibitory activity of the Portuguese wild mushroom Clitocybe alexandri in human tumour cell lines|
|Autor: ||Vaz, Josiana A.|
Almeida, Gabriela M.
Vasconcelos, M. Helena
Ferreira, Isabel C.F.R.
|Issue Date: ||2010|
|Citação: ||Vaz, Josiana A.; Almeida, Gabriela M.; Martins, Anabela; Vasconcelos, M. Helena; Ferreira, Isabel C.F.R. (2010) - In vitro growth inhibitory activity of the Portuguese wild mushroom Clitocybe alexandri in human tumour cell lines. In 2º Encontro Nacional de Química Terapêutica. Porto|
|Resumo: ||Some mushrooms are a powerful source of bioactive compounds. lndeed, many pre-clinical
studies have been conducted in human tumour cell lines and in some cases a number of
compounds extracted from mushrooms have entered clinical trials . Our previous results
showed that phenolic (methanolic and ethanolic) and polissacharidic extracts from Clitocybe
alexandri inhibited the growth of four human cell lines (lung, breast, colon and gastric cancer) .
The aim of the present work was to: i) further elucidate the mechanism of action of the ethanolic
extract that leads to the observed cell growth inhibition, by analysing the cell cycle profile of the
NCI-H460 cells treated with this extract and ii) identify and quantify the chemical compounds
present in the phenolic and polissacharidic extracts.|
|Arbitragem científica: ||yes|
|Appears in Collections:||BB - Resumos em Proceedings Não Indexados ao ISI/Scopus|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.