Biblioteca Digital do Instituto Politécnico de Bragança   Instituto Politécnico de Bragança

Biblioteca Digital do IPB >
Escola Superior Agrária >
Biologia e Biotecnologia >
BB - Resumos em Proceedings Não Indexados ao ISI/Scopus >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10198/3366

Título: In vitro growth inhibitory activity of the Portuguese wild mushroom Clitocybe alexandri in human tumour cell lines
Autor: Vaz, Josiana A.
Almeida, Gabriela M.
Martins, Anabela
Vasconcelos, M. Helena
Ferreira, Isabel C.F.R.
Issue Date: 2010
Citação: Vaz, Josiana A.; Almeida, Gabriela M.; Martins, Anabela; Vasconcelos, M. Helena; Ferreira, Isabel C.F.R. (2010) - In vitro growth inhibitory activity of the Portuguese wild mushroom Clitocybe alexandri in human tumour cell lines. In 2º Encontro Nacional de Química Terapêutica. Porto
Resumo: Some mushrooms are a powerful source of bioactive compounds. lndeed, many pre-clinical studies have been conducted in human tumour cell lines and in some cases a number of compounds extracted from mushrooms have entered clinical trials [1]. Our previous results showed that phenolic (methanolic and ethanolic) and polissacharidic extracts from Clitocybe alexandri inhibited the growth of four human cell lines (lung, breast, colon and gastric cancer) [2]. The aim of the present work was to: i) further elucidate the mechanism of action of the ethanolic extract that leads to the observed cell growth inhibition, by analysing the cell cycle profile of the NCI-H460 cells treated with this extract and ii) identify and quantify the chemical compounds present in the phenolic and polissacharidic extracts.
Arbitragem científica: yes
URI: http://hdl.handle.net/10198/3366
Appears in Collections:BB - Resumos em Proceedings Não Indexados ao ISI/Scopus

Files in This Item:

File Description SizeFormat
Nac_47.pdf689,17 kBAdobe PDFView/Open

Please give feedback about this item
Statistics
FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpaceOrkut
Formato BibTex mendeley Endnote Logotipo do DeGóis 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 


© Instituto Politécnico de Bragança - Biblioteca Digital - Feedback - Statistics
Promotores do RCAAP   Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência PO Sociedade do Conhecimento (POSC) Portal oficial da União Europeia