Utilize este identificador para referenciar este registo: http://hdl.handle.net/10198/13012
Título: Grafting of functional brushes on the surface of 5-Fluorouracil molecularly imprinted polymer particles through RAFT polymerization
Autor: Dias, Rolando
Costa, Mário
Palavras-chave: Molecular imprinting
RAFT polymerization
Surface grafting
Data: 2016
Citação: Oliveira, Daniela; Dias, Rolando; Costa, Mário (2016) - Grafting of functional brushes on the surface of 5-Fluorouracil molecularly imprinted polymer particles through RAFT polymerization. In 12th International Workshop on Polymer Reaction Engineering. University of Hamburg, Germany
Resumo: The grafting of functional brushes on the surface of molecularly imprinted polymer (MIP). particles hás been explored in the last few years to synthesize materiais combining high molecular recognition capabilities and stimulation triggered by changes in the surrounding environment [1, 2]. In the present work, MIP particles for 5-fluorouracil (a drug used in câncer treatment) were produced by precipitation polymerization in acetonitrile, using either MAA or HEMA as imprinting fünctional monomers, and m the presence of different kinds of RAFT agents. In a second step, taking advantage of the RAFT groups present in the surface of the particles, different kinds of fiinctional polymer brushes were grafted on the MIPs considering a "grafting from" process in the presence of a RAFT agent.
Peer review: yes
URI: http://hdl.handle.net/10198/13012
Aparece nas colecções:DTQB - Resumos em Proceedings Não Indexados ao ISI/Scopus

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