Utilize este identificador para referenciar este registo: http://hdl.handle.net/10198/10150
Título: Bioactivity of different enriched phenolic extracts of wild fruits from Northeastern Portugal: a comparative study
Autor: Guimarães, Rafaela
Barros, Lillian
Calhelha, Ricardo C.
Carvalho, Ana Maria
Queiroz, Maria João R.P.
Ferreira, Isabel C.F.R.
Palavras-chave: Wild fruits
Northeastern Portugal
Phenolic compounds
Antioxidant activity
Antitumor effects
Data: 2014
Editora: Springer
Citação: Guimarães, Rafaela; Barros, Lillian; Calhelha, Ricardo C.; Carvalho, Ana Maria; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R. (2014) - Bioactivity of different enriched phenolic extracts of wild fruits from Northeastern Portugal: a comparative study. Plant Foods for Human Nutrition. ISSN 0921-9668. 69:1, p. 37-42
Resumo: Arbutus unedo, Prunus spinosa, Rosa micrantha and Rosa canina are good sources of phenolic compounds, including anthocyanins. These compounds have potent antioxidant properties, which have been related to anticancer activity. Herein, the in vitro antioxidant and antitumor properties of enriched phenolic extracts (non-anthocyanin phenolic compounds enriched extract- PE and anthocyanins enriched extract- AE) of the mentioned wild fruits were evaluated and compared. PE gave higher bioactive properties than the corresponding AE. It was observed a high capacity of A. unedo phenolic extract to inhibit lipid peroxidation in animal brain homogenates (EC50 = 7.21 µg/mL), as also a high antitumor potential against NCI-H460 human cell line (non-small lung cancer; GI50 = 37.68 µg/mL), which could be related to the presence of galloyl derivatives (exclusively found in this species). The bioactivity of the studied wild fruits proved to be more related to the phenolic compounds profile than to the amounts present in each extract, and could be considered in the design of new formulations of dietary supplements or functional foods.
Peer review: yes
URI: http://hdl.handle.net/10198/10150
DOI: 10.1007/s11130-013-0394-5
ISSN: 0921-9668
Aparece nas colecções:CIMO - Artigos em Revistas Indexados à WoS/Scopus

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