Utilize este identificador para referenciar este registo: http://hdl.handle.net/10198/10148
Título: Antifungal activity of phenolic compounds identified in flowers from North Eastern Portugal against Candida species
Autor: Alves, Carlos Tiago
Ferreira, Isabel C.F.R.
Barros, Lillian
Silva, Sónia
Azeredo, Joana
Oliveira, Rosário
Henriques, Mariana
Data: 2014
Citação: Alves, Carlos Tiago; Ferreira, Isabel C.F.R.; Barros, Lillian; Silva, Sónia; Azeredo, Joana; Oliveira, Rosário; Henriques, Mariana (2014) - Antifungal activity of phenolic compounds identified in flowers from the North Eastern Portugal against Candida species. Future Microbiology. ISSN 1746-0913. 9:2, p. 139-146
Resumo: To evaluate the antifungal effect of gallic acid, catechin, luteolin and quercetin, phenolic compounds identified from flowers of North Eastern Portugal, against Candida planktonic and biofilm cells. Materials & methods: The MICs were determined in Candida planktonic cells and the effect of phenolic compounds on Candida biofilms was assessed through quantification of CFUs. Results: MIC values demonstrated that gallic acid presented the highest effect against all Candida species. Catechin showed a similar effect against Candida albicans American Type Culture Collection (ATCC) 90028 cells. In addition, gallic acid and quercetin had demonstrated only a minimal effect against Candida species biofilms. Conclusion: Gallic acid affected the growth of the different planktonic Candida species in all concentrations used; still, catechin showed a similar effect against C. albicans ATCC 90028 and Candida glabrata ATCC 2001 cells. In addition, only gallic acid and quercetin demonstrated a slight effect against all Candida species biofilms.
Peer review: yes
URI: http://hdl.handle.net/10198/10148
DOI: 10.2217/fmb.13.147
ISSN: 1746-0913
Aparece nas colecções:CIMO - Artigos em Revistas Indexados à WoS/Scopus

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