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Browsing by Author Abreu, Rui M.V.

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Issue DateTitleAuthor(s)
20111-aryl-3-(4-(7-methylthieno[3,2-d]pyrimidin-4-yloxy)phenyl)ureas: synthesis and molecular modelling studies using VEGFR-2Soares, Pedro; Froufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Borges, Fernanda; Queiroz, Maria João R.P.
20111-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as potential inhibitors of VEGFR-2: synthesis and molecular modelling studiesSoares, Pedro; Froufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Borges, Fernanda; Queiroz, Maria João R.P.
20121-Aryl-3-[ 4-( thieno[3,2-d]pyrimidin-4-yloxy )phenyl]ureas as VEG FR2 inhibitors: synthesis, docking enzymatic and cellular assaysPeixoto, Daniela; Calhelha, Ricardo C.; Soares, Pedro; Abreu, Rui M.V.; Froufe, Hugo J.C.; Ferreira, Isabel C.F.R.; Costa, Raquel; Soares, Raquel; Queiroz, Maria João R.P.
20131-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR-2 tyrosine kinase inhibitors: Synthesis, biological evaluation, and molecular modelling studiesSoares, Pedro; Costa, Raquel; Froufe, Hugo J.C.; Calhelha, Ricardo C.; Peixoto, Daniela; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Soares, Raquel; Queiroz, Maria João R.P.
20121-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assaysQueiroz, Maria João R.P.; Peixoto, Daniela; Soares, Pedro; Abreu, Rui M.V.; Froufe, Hugo J.C.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Costa, Raquel; Soares, Raquel
2012Aminodi(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, effects in human tumor cells growth, cell cycle analysis, apoptosis and evaluation of toxicity using non-tumor cells.Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Peixoto, Daniela; Abreu, Rui M.V.; Vale-Silva, Luís A.; Pinto, Eugénia; Lima, Raquel T.; Alvelos, M. Inês; Vasconcelos, M. Helena; Queiroz, Maria João R.P.
2011Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2- carboxylate derivatives: In vitro evaluation, cell cycle analysis and QSAR studiesAbreu, Rui M.V.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Lima, Raquel T.; Vasconcelos, M. Helena; Adega, Filomena; Chaves, Raquel; Queiroz, Maria João R.P.
2013Antimicrobial activity of phenolic compounds identified in wild mushrooms, SAR analysis and docking studiesAlves, Maria José; Ferreira, Isabel C.F.R.; Froufe, Hugo J.C.; Abreu, Rui M.V.; Martins, Anabela; Pintado, Manuela
2009Antioxidants in wild mushroomsFerreira, Isabel C.F.R.; Barros, Lillian; Abreu, Rui M.V.
2010Anti-proliferative activity of thieno[3,2-b]pyridine derivatives in tumoral and primary hepatic cell lines.Abreu, Rui M.V.; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.; Adega, Filomena; Chaves, Raquel
2013Aplicação de ferramentas de quimioinformática no desenvolvimento de novos fármacos: tienopiridinas como inibidores de VEGFR-2Abreu, Rui M.V.; Froufe, Hugo J.C.; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.
2011Chemical, biochemical and electrochemical assays to evaluate antioxidant properties of three new diarylamines in the thieno[3,2-b]pyridine series.Calhelha, Ricardo C.; Abreu, Rui M.V.; Vilas-Boas, Miguel; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.
2011ChemT, an open-source software for building template-based chemical librariesAbreu, Rui M.V.; Froufe, Hugo J.C.; Daniel, Pedro O.M.; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.
2010ChemT, a software for building template-based 3D chemical libraries.Abreu, Rui M.V.; Froufe, Hugo J.C.; Daniel, Pedro O.M.; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.
2008A convenient high performance computing (HPC) methodology for virtual screening using Autodock 4Abreu, Rui M.V.; Froufe, Hugo J.C.; Ferreira, Isabel C.F.R.; Queiroz, Maria João R.P.
2012Crataegus monogyna buds and fruits phenolic extracts: growth inhibitory activity on human tumor cell lines and chemical characterization by HPLC–DAD–ESI/MSRodrigues, Sandra; Calhelha, Ricardo C.; Barreira, João C.M.; Dueñas, Montserrat; Carvalho, Ana Maria; Abreu, Rui M.V.; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.
2011Desenvolvimento de ferramentas de bioinformática para aplicação em Química Medicinal: MOLA e ChemT.Abreu, Rui M.V.; Froufe, Hugo J.C.; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.
2014Docking studies in target proteins involved in mechanisms of antibacterial action: extending the knowledge on standard antibiotics to mushrooms antimicrobial compoundsAlves, Maria José; Froufe, Hugo J.C.; Costa, Ana F.T.; Santos, Anabela F.; Oliveira, Liliana G.; Osório, Sara R.M.; Abreu, Rui M.V.; Pintado, Manuela; Ferreira, Isabel C.F.R.
2012Docking studies to evaluate mushrooms low molecular weight compounds as inhibitors of the anti-apoptotic protein BCL-2Froufe, Hugo J.C.; Abreu, Rui M.V.; Barros, Lillian; Ferreira, Isabel C.F.R.
2010Docking studies using proteins involved in breast cancer and low molecular weight compounds found in wild mushroomsFroufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.
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