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Flow of red blood cells suspensions through hyperbolic microcontractions

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The present study uses a hyperbolic microchannel with a low aspect ratio (AR) to investigate how the red blood cells (RBCs) deform under conditions of both extensional and shear induced flows. The deformability is presented by the degree of the deformation index (DI) of the flowing RBCs throughout the microchannel at its centerline. A suitable image analysis technique is used for semi-automatic measurements of average DIs, velocity and strain rate of the RBCs travelling in the regions of interest. The results reveal a strong deformation of RBCs under both extensional and shear stress dominated flow conditions.

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Faustino, Vera; Pinho, Diana; Yaginuma, Tomoko; Calhelha, Ricardo C.; Kim, Geyong; Arana, Sergio; Ferrreira, Isabel C.F.R.; Oliveira, Mónica S. N.; Lima, R. (2013). Flow of red blood cells suspensions through hyperbolic microcontractions. In Cap. 9 de Visualization and Simulation of Complex Flows in Biomedical Engineering. Springer, p. 151-163. ISBN 978-94-007-7768-2

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Springer

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