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Advisor(s)
Abstract(s)
Chromones are a well-known class of naturally occurring oxygencontaining
heterocyclic compounds; many of them playing important
biological functions in nature [1]. Although 2-methylchromones are one
of the scarcest classes of natural chromones, their synthesis and
reactivity is well studied. They can participate in several chemical
transformations such as oxidation, thiation, hydrogenation, photolysis,
cycloaddition and condensation reactions, being useful targets in the
synthesis of novel heterocyclic compounds [2]. The acidity of the 2-
methyl group, due to the low electron density at C-2 caused by oxygen
atom and the α,β-unsaturated ketone system, led us to explore the
condensation of 2-methylchromones [3] with propargyl aldehydes [4].
Description
Keywords
Citation
Albuquerque, Hélio; Santos, Clementina M. M.; Silva, Artur; Cavaleiro, José A. S. (2013). Synthesis of (E)-2-(4-Arylbut-1-en-3-ynyl)-4H-chromen-4-ones. In XXIII Encontro Nacional da Sociedade Portuguesa de Química. Aveiro
Publisher
Universidade de Aveiro