| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 244.3 KB | Adobe PDF |
Orientador(es)
Resumo(s)
Gram positive (Bacillus cereus, B. subtilis), Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria, and Candida albicans as a representative of fungi were used for screening the in vitro antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[
b]thiophene series bearing different substituents, synthesized by us using the palladium-catalyzed C–N coupling
methodology. The minimal inhibitory concentration (MIC) and structure–activity relationships (SARs) were evaluated.
Descrição
Palavras-chave
Diarylamines Antimicrobial activity SAR Benzothiophenes
Contexto Educativo
Citação
Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Leticia M.; Queiroz, Maria João R.P. (2004). Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study. Bioorganic & Medicinal Chemistry Letters. ISSN 0960-894X. 14:23, p. 5831-5833
Editora
Elsevier