Autores
Calhelha, Ricardo C.
Ferreira, Isabel C.F.R.
Abreu, Rui M.V.
Orientador(es)
Resumo(s)
Several series of compounds that include the
thienopyridine scaffold have been reported as
inhibitors of known cancer therapeutic targets or
as inhibitors of cell proliferation in tumor cell lines
[1,2]. Our research group has already
synthesized several thieno[3,2-b]pyridine
derivatives by Pd-catalyzed C-C (Suzuki and
Sonogashira) and C-N (Buchwald-Hartwig)
couplings and some of them have presented
tumor cell growth inhibitory activity in cell lines [3-
5].
Descrição
Palavras-chave
Contexto Educativo
Citação
Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Abreu, Rui M.V.; Vale-Silva, Luís A.; Pinto, Eugénia; Lima, Raquel T.; Alvelos, M. Inês; Vasconcelos, M. Helena; Queiroz, Maria-João R.P. (2011). Synthesis of aminodiarylamines in the thieno[3,2-b]pyridine series and effects on tumor cell growth inhibition, cell cycle and apoptosis. In III Congress of the Portuguese Society of Pharmaceutical Sciences and IX Spanish-Portuguese conference on controlled drug delivery. Porto
Editora
Sociedade Portuguesa de Ciências Farmacêuticas