Microscale flow dynamics of red blood cells in a circular microchannel

The blood flow dynamics in microcirculation depends strongly on the motion, deformation and interaction of RBCs within the microvessel. This paper presents the application of a confocal micro-PTV system to track RBCs through a circular polydimethysiloxane (PDMS) microchannel. This technique, consists of a spinning disk confocal microscope, high speed camera and a diode-pumped solid state (DPSS) laser combined with a single particle tracking (SPT) method. By using this system detailed motions of individual RBCs were measured at a microscale level. Our results showed that this technique can provide detailed information about microscale disturbance effects caused by RBCs in flowing blood.

Keywords

Blood flow Microcirculation

URI

http://hdl.handle.net/10198/4981

Citation

Lima, Rui; Nakamura, M.; Ishikawa, T.; Tanaka, S.; Takeda, M.; Imai, Y.; Tsubota, K.; Wada, S.; Yamaguchi, T. (2008). Microscale flow dynamics of red blood cells in a circular microchannel. COMPUTATIONAL VISION AND MEDICAL IMAGING PROCESSING. ISBN 978-0-415-45777-4.