Experiments on computer assisted optimization of the escherichia coli fermentation process using Optferm

Teixeira, Tânia; Deusdado,  Sérgio

http://hdl.handle.net/10198/4378

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Authors

Teixeira, Tânia

Deusdado, Sérgio

Abstract(s)

We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesses avoiding expensive experiments.

Keywords

Bioprocesses optimization Bioprocesses modeling

URI

http://hdl.handle.net/10198/4378

Citation

Teixeira, Tânia; Deusdado, Sérgio (2011). Experiments on computer assisted optimization of the escherichia coli fermentation process using Optferm. In Rocha, Miguel P.[e tal.] 5th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2011). Berlin: Springer-Verlag. p. 79-82. (Advances in Intelligent and Soft Computing; 93). ISBN 978-3-642-19913-4