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Advisor(s)
Abstract(s)
Disruption of the balance between reactive oxygen species (ROS) production
and elimination leads to oxidative stress. ROS are known for being implicated in
many cell disorders and in the development of many diseases including
cardiovascular diseases, cancer, atherosclerosis, cataracts, chronic inflammation
or neurodegenerative diseases. Some of these diseases seem to have the same
underlying mechanisms, depending on oxidative processes leading to products
with reactive properties, affecting specific molecular targets in the vascular
system, and cellular DNA.1 To find new natural sources o f bioactive
compounds, the antioxidant properties of almond green barks and fruits,
chestnut skins, leaves and fruits, were evaluated through chemical and
biochemical assays: 2,2-diphenyl- 1-picrylhydrazyl radical scavenging activity,
reducing power, inhibition of P-carotene bleaching, inhibition of oxidative
hemolysis in erythrocytes induced by 2,2 -azobis(2-amidinopropane)dihydrochloride
and inhibition of lipid peroxidation in brain tissue (formation of
thiobarbituric acid reactive substances).
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Keywords
Citation
Barreira, João C.M.; Ferreira, Isabel C.F.R.; Oliveira, M. Beatriz P.P.; Pereira, José Alberto (2008). Radical scavenging activity and lipid peroxidation inhibition of almond, chestnut and their by-products: a comparative study. In XVI Congresso Nacional de Bioquímica. Ponta Delgada