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Resumo(s)
Thienocarbazoles are bioisosters of anti-tumoural pyridocarbazoles, ellipticine and olivacine.
Methylated thienocarbazoles 1 were synthesized by reductive cyclization of 6-(2'nitrophenyl)
benzo[b]thiophenes 2, using triethylphosphite. Compounds 2 were obtained by
palladium-catalyzed cross-coupling between 2-bromo or iodonitrobenzenes and 6-boronic
esters of methylated benzo[b]thiophenes (communication presented at this meeting).
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Citação
Ferreira, Isabel C.F.R.; Queiroz, Maria-João R.P.; Kirsch, Gilbert (2000) – Synthesis of thienocarbazoles by reductive cyclization of 6-(2’- nitrophenyl)benzo[b]thiophenes. In XIX th European Colloquium on Heterocyclic Chemistry. Aveiro