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Advisor(s)
Abstract(s)
Detailed knowledge on the motion of individual red blood cells
(RBCs) flowing in microchannels is essential to provide a better
understanding on the blood rheological properties and disorders in
microvessels. Several studies on both individual and concentrated
RBCs have already been performed in the past. However, all
studies used conventional microscopes and also ghost cells to obtain
visible trace RBCs through the microchannel. Recently, considerable
progress in the development of confocal microscopy and consequent
advantages of this microscope over the conventional microscopes have
led to a new technique known as confocal micro-PIV. This
technique combines the conventional PIV system with a spinning disk
confocal microscope (SDCM). Due to its outstanding spatial filtering
technique together with the multiple point light illumination system,
this kind of microscope has the ability to obtain in-focus images with
optical thickness less than 1 μm, a task extremely difficult to be
achieved by using a conventional microscope.
The main purpose of this paper is to investigate the ability of our
confocal micro-PTV system to measure the motion of individual RBCs
at different haematocrit (Hct) through microchannels.
Description
Keywords
Erythrocyte Microchannel Micro-PTV Microcirculation
Citation
Lima, R.; Ishikawa, T.; Takeda, M.; Tanaka, S.; Imai, Y.; Tsubota, K.; Wada, S.; Yamaguchi, T. (2007). Measurement of erythrocyte motions in microchannels by using a confocal micro-PTV system. In ASME Summer Bioengineering Conference. Colorado, USA.