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Advisor(s)
Abstract(s)
The need to analyse the microscopic mechanical behaviour of blood flow was one of the main
reasons to develop a new computer simulation using a particle method. This new mesh free
method is based on a moving-particle semi-implicit (MPS) method, which has been developed
to simulate incompressible fluids based on the Navier-Stokes equations. The simulation region
was discretized by particles that moves in Lagrangian coordinates, where the plasma and
platelets were modelled as fluid particles, red blood cells (RBC) as elastic particles and vessel
wall as rigid particles. In this paper, some applications of the MPS method to study the blood
flow are briefly analysed, such as the motion and deformation of red blood cells (RBC) in
plasma flow and the platelet aggregation process in blood flow. Some preliminary studies
suggest that there is evidence that the proposed method enables the analysis of the RBC
motion and deformation in the plasma flow and also the initial thrombogenesis, growth and
destruction of thrombus.
Description
Keywords
Particle method Blood flow MPS method Red blood cells
Citation
Lima, R.; Kitagawa, Y.; Kamada, H.; Tsubota, K.; Wada, S.; Yamaguchi, T. (2005). A particle method computer simulation: applications to the study of blood flow. In 1º Encontro de Biomecânica. Abrantes. ISBN 972-789-151-9
Publisher
Sociedade Portuguesa de Biomecânica