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Advances in simulated moving bed chromatographic separations

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The development of some unconventional Simulated Moving Bed (SMB) strategies, such as the introduction of nonsynchronous inlet/outlet shifts (the Varicol process), variable flux or variable composition in the inlet/outlet streams (PowerFeed and Modicon, respectively), and also the use of multiple feed or distributed feed, have increased the potential of this technique for a wide range of binary separations. For multiple component separations, different strategies has been investigated, including a cascade of SMB, more complex SMB units composed by several adsorption zones, and the JO process operating in two different separation steps.

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Simulated moving bed Modeling and simulation Varicol Multiple feed

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Gomes, P. Sá; Minceva, M.; Pais, L.S.; Rodrigues, A.E. (2006). Advances in simulated moving bed chromatographic separations. In Chiral Separation Techniques. [S.l.]: Wiley. p. 181-202. ISBN 9783527315093.

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Wiley

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