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Coleostephus myconis (L.) Rchb.f. is a rich source of phenolic acids which are possibly associated
with its high antioxidant activity. In the present study, hydroethanolic extracts from two different
botanical parts of C. myconis (senescent flowers; green parts) were incorporated into hydrosoluble
gels. Bearing in mind the EC50 values from previous antioxidant activity evaluation assays, gels were
prepared using a concentration of 0.25 mg/mL (senescent flowers) and 0.50 mg/mL (green parts).
Since the inclusion of parabens is nowadays poorly accepted by the consumers, imidazolidinyl urea
was included as the antimicrobial component. Gels had a non-greasy texture and good dermic
absorption dynamics. Regarding pH evaluation, there were no significant alterations during the 180
days of observation (5.5 and 6.5). The antioxidant activity of the prepared hydrogels was assessed
and compared with a blank formulation and also with the results obtained for the extracts alone. The
antioxidant activity measured in each hydrosoluble gel was very similar to the value obtained for the
isolated extract, in what regards TBARS and β-carotene bleaching inhibition, DPPH and reducing
power, thereby indicating the suitability of the C. myconis extract to prepare this type of
dermocosmetic products.
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Citação
Bessada, Sílvia; Barreira, João C.M.; Oliveira, M.B.P.P.; Ferreira, Isabel C.F.R. (2016). Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application. In 9th Meeting of Young Researchers of University of Porto. Porto