SMB units using a low number of chromatographic columns

Pais, Luís S.; Rodrigues, Alírio

http://hdl.handle.net/10198/1602

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Authors

Pais, Luís S.

Rodrigues, Alírio

Abstract(s)

Simulated Moving Bed (SMB) chromatography has received significant attention in the last decade, particularly in the production of high valuable products, such as enantiomerically pure pharmaceutical compounds. Recent applications in the pharmaceutical industry use SMB systems containing a low total number of columns, usually four to eight. The objective of this work is to compare the performance of SMB systems with a low number of columns.

Keywords

Simulated moving bed Modeling and simulation Low number of columns

URI

http://hdl.handle.net/10198/1602

Citation

Pais, L.S.; Rodrigues, A.E.; (2001). SMB units using a low number of chromatographic columns. In Separations Technology Topical Conference, AIChE Annual Meeting. 150:II, p.683-688