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Separation of enantiomers by SMB chromatography: strategies of modeling and process performance

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04. 1998 FA6 actas.pdf3.04 MBAdobe PDF Download

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The paper deals with chiral separation by Simulated Moving Bed chromatography. A package for SMB simulation based on the analogy with the true moving bed is described. The package allows the prediction of regions for enantiomers separation. The influence of mass transfer resistance in the separation region is analyzed. A practical tool for choosing the better SMB operating conditions as a function of the feed flow rate is proposed.

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Simulated moving bed Modeling and simulation Separation regions Mass transfer resistance

Citation

Pais, L.S.; Rodrigues, A.E. (1998). Separation of enantiomers by SMB chromatography: strategies of modeling and process performance. In Fundamentals of Adsorption 6: Proceedings of the Sixth International Conference of Fundamentals of Adsorption. Paris. p.371-376

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Francis Meunier (ed.)

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