Chiral separation by simulated moving bed chromatography: comparison between configurations using a low number of columns

Pais, Luís S.; Rodrigues, Alírio

http://hdl.handle.net/10198/1582

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Authors

Pais, Luís S.

Rodrigues, Alírio

Abstract(s)

Recent applications in the pharmaceutical industry use SMB systems containing a low total number of columns, usually four to eight. The objective of this work is to evaluate and compare the performance of SMB systems with a low number of columns. Simulation results will be shown for SMB units with 4, 5, and 6 columns. Also the two strategies of modeling, TMB and SMB, will be compared for these configurations.

Keywords

Simulated moving bed Modeling and simulation Low number of columns

URI

http://hdl.handle.net/10198/1582

Citation

Pais, L.S.; Rodrigues, A.E. (2001). Chiral separation by simulated moving bed chromatography: comparison between configurations using a low number of columns. In 8th International Chemical Engineering Conference. CHEMPOR’. Aveiro. p.1201-1206