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Publication
Conjugate additions of carbon nucleophiles to chromone derivatives towards nitrogen heterocycles
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Advisor(s)
Abstract(s)
Conjugate additions of
nitromethane to the extended π-
system of chromone derivatives
afforded the 1,6-conjugate
addition products, together with
structure complex oxygen
heterocycles through tandem
processes. Further
functionalization of targeted
adducts allowed the preparation
of biological relevant nitrogen
heterocycles such as
styrylpyrrolidines, as well as
pyrazole and bis-pyrazole
derivatives.
Description
Keywords
Pedagogical Context
Citation
Albuquerque, Hélio; Santos, Clementina M.M.; Cavaleiro, José; Silva, Artur (2017). Conjugate additions of carbon nucleophiles to chromone derivatives towards nitrogen heterocycles. In Research Day. Aveiro