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Advisor(s)
Abstract(s)
The objective of this work is to develop a novel coacervation process to produce microcapsules of
polylactide (PLA) to encapsulate thyme oil that will be used in cosmetics. The novelty of this approach
consists of dissolving PLA in dimethylformamide (DMF) which is a good solvent for PLA but in addition has
high solubility in water. Upon contact with water, the homogeneous solution of PLA in DMF promotes the
precipitation of PLA around the thyme oil core. The produced microcapsules have bimodal particle size
distributions in volume with a mean particle size of 40 mm. Microcapsules analysis by microscopy have
confirmed the spherical shape, the rough surface and allowed the estimation of the wall thickness around
5 mm. Quantification of the encapsulated thyme oil was performed by gas chromatography and allowed
to evaluate the quality of the encapsulated oil and pointed out for a preferential encapsulation of thyme
oil apolar compounds.
Description
Keywords
Microcapsules Coavervation PLA Thyme oil
Citation
Martins, I.M.; Rodrigues, S.N.; Barreiro, M.F.; Rodrigues, A.E. (2009). Microencapsulatin of thyme oil by coacervation. Journal of Microencapsulation. ISSN 1464-5246. 26:8 p.667-675