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Advisor(s)
Abstract(s)
The screening of different solvents and solvents mixtures for the
analytical and preparative separation of nadolol stereoisomers
using two chiral stationary phases is presented.
The experimental results are analysed through different
strategies of liquid chromatographic separation depending on the
target compound to be separated from a quaternary chiral
racemic mixture.
The wide range of present results can be very useful both for the
analytical or preparative separation of nadolol in order to better
characterize the pharmacological and therapeutical behaviour of
all single stereoisomers of this beta-blocker pharmaceutical drug.
Description
Keywords
Citation
Ribeiro, A.E. Rodrigues, A.E., and Pais, L.S. (2014). Optimization of the adsorption process for the analytical and preparative separation of nadolol stereoisomers. In CHEMPOR 2014 12th International Chemical and Biological Engineering Conference. Porto