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Modeling strategies for enantiomers separation by SMB chromatography

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04. 1998 AIChEJ.pdf768.43 KBAdobe PDF Ver/Abrir

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Resumo(s)

Modeling strategies for simulated moving bed adsorbers were studied to compare the simulated moving bed model (SMB) that considers the real shift of the injection and collection points to the true moving bed approach (TMB) that considers liquid and solid flow in opposite directions. The prediction of these two models is compared in terms of steady-state performance, steady-state internal concentration profiles, and transient behavior of the extract and raffinate purities. The influence of the degree of subdivision of the bed in the SMB model predictions is also analyzed and compared with the TMB performance. Model results are compared with experimental results obtained for the chromatographic separation of binaphthol enantiomers.

Descrição

Palavras-chave

Simulated moving bed chromatography Modeling and Simulation Chiral separation

Contexto Educativo

Citação

Pais, L.S.; Loureiro, J.M.; Rodrigues, A.E. (1998). Modeling strategies for enantiomers separation by SMB chromatography. AIChE Journal. ISSN 1547-5905. 44:3, p.561-569

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Fascículo

Editora

Wiley

Licença CC

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