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Advisor(s)
Abstract(s)
Alzheimer’s Disease (AD) is a chronic progressive and irreversible neurodegenerative brain disorder. The
aging population has been increasing significantly in recent decades. Therefore, AD will continue to increase
because the disease affects mainly the elderly. Its diagnostic accuracy is relatively low, and there is not a
biomarker able to detect AD without invasive tests. The electroencephalogram (EEG) test is a widely available
technology in clinical settings. It may help diagnosis of brain disorders, once it can be used in patients who
have cognitive impairment involving a general decrease in overall brain function or in patients with a located
deficit. This study is a new approach to detect EEG temporal events in order to improve the AD diagnosis.
For that, K-means and Self-Organized Maps were used, and the results suggested that there are sequences of
EEG energy variation that appear more frequently in AD patients than in healthy subjects.
Description
Keywords
Alzheimer’s disease Sequences Self-organized maps Temporal events K-means Electroencephalogram (EEG)
Citation
Rodrigues, P. M.; Freitas, D.; Teixeira, João Paulo (2013). Detection of alzheimer’s disease electroencephalogram temporal events. International Journal of Reliable and Quality E-Healthcare. ISSN 2160-9551. 2:3, p 44-61