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Abstract(s)
Os enzimas lipases (E.C.3.1.1.3) pertencem à família das serinas hidrolases, que por sua vez incluem várias enzimas esterases (E.C.3.1.1.1). Uma característica que distingue as lipases das esterases é o facto de serem capazes de realizar a hidrólise de óleos e gorduras em glicerol e ácidos gordos livres na interface óleo-água. Normalmente é aceite que as esterases hidrolisam ligações éster em esteres e triacilgliceróis de cadeia carbónica curta, libertando ácidos gordos de baixo peso molecular, já as lipases hidrolisam preferencialmente triacilglicerois de cadeia longa. As lipases microbianas apresentam uma grande diversidade de aplicações industriais tais como na indústria farmacêutica, alimentar, de detergentes entre outros.
The enzyme lipase (EC3.1.1.3) belongs to the family of serine hydrolases, which in turn to include various enzymes esterase (EC3.1.1.1). One feature that distinguishes lipases from esterases is the fact that they are capable of performing the hydrolysis of oils and fats into glycerol and free fatty acids in the oil-water interface. It is usually accepted that the esterases hydrolyze ester bonds in stacked short carbon chain triacylglycerols, releasing fatty acids of low molecular weight, since lipases hydrolyze long chain triacylglycerols preferentially. Microbial lipases have a wide variety of industrial applications such as in pharmaceuticals, food, detergent and more.
The enzyme lipase (EC3.1.1.3) belongs to the family of serine hydrolases, which in turn to include various enzymes esterase (EC3.1.1.1). One feature that distinguishes lipases from esterases is the fact that they are capable of performing the hydrolysis of oils and fats into glycerol and free fatty acids in the oil-water interface. It is usually accepted that the esterases hydrolyze ester bonds in stacked short carbon chain triacylglycerols, releasing fatty acids of low molecular weight, since lipases hydrolyze long chain triacylglycerols preferentially. Microbial lipases have a wide variety of industrial applications such as in pharmaceuticals, food, detergent and more.
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Citation
Vaz, Madalena; Choupina, Altino (2012). Lipases: biocatalizadores da hidrólise de triacilglicerois. Revista Eletrônica de Biologia. ISSN 1983-7682. 5:3, p. 42-58
Publisher
PUC-SP: Pontificia Universidade Católica de S.Paulo, Brasil