Solubility of flavonoids in pure and mixed solvents

Ferreira, Olga; Pinho, Simão

http://hdl.handle.net/10198/10525

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Authors

Ferreira, Olga

Pinho, Simão

Abstract(s)

Flavonoids are receiving considerable attention due to their important biological and pharmacological properties [1]. In particular, the systematic study of their solubility in liquid halls is being presented in the literature [2-8] to support the design of extraction, precipitation or cristallization processes. These compounds have a complex structure with a variety of functional groups that makes them difficu lt to represent by traditional thermodynamic models. This work is divided in two parts. In the experimental section. new solubility data is presented for hesperetin in several pure and mixed solvents at different temperatures. The shake-flask methods is applied, followed by quantitative analysis.